Reports and Surveys | January 22, 2026

A Cost-Benefit Analysis of GLP-1s

We conducted a cost-benefit analysis of glucagon-like peptide-1 agonists (GLP-1s) using data from SHAPE, our proprietary health data warehouse. We looked at utilization of GLP-1s for both diabetes and weight loss and the impact on health plans.

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We found:

  • Adherence with GLP-1 therapy differs for diabetics and those using the medication for weight loss.
  • Adherence also differs among age groups and between men and women.
  • Adherence rates have a significant impact on savings.

How does your plan’s experience with GLP-1 utilization compare?

You can use SHAPE data to benchmark your plan’s experience and performance.

SHAPE includes information from large health plans across the United States representing a range of industries and organizations. Collectively, they cover more than four million lives.

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Interested in mining your own health plan data and/or benchmarking it?

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This page is for informational purposes only and does not constitute legal, tax or investment advice. You are encouraged to discuss the issues raised here with your legal, tax and other advisors before determining how the issues apply to your specific situations.